Kalanchoe pinnata, commonly known as the “Wonder Plant,” is a tropical succulent widely recognized for its broad spectrum of pharmacological activities and rich phytochemical profile. This review summarizes the phytochemical constituents and therapeutic potentials of K. pinnata as documented in various scientific studies. The plant demonstrates significant antimicrobial, anticancer, anti-inflammatory, antidiabetic, and wound-healing properties, largely attributed to its abundance of flavonoids, phenols, alkaloids, vitamins, and other bioactive compounds. These findings highlight its value in traditional medicine and support continued research into its pharmacological applications.