Recurrent miscarriage is a significant reproductive health issue, with antiphospholipid antibodies emerging as a key factor in its pathophysiology. This study aims to explore the prevalence and impact of anticardiolipin antibodies as antiphospholipid antibodies among Sudanese women with recurrent miscarriages attending the Teaching Hospital of Kosty, White Nile, Sudan. A total of 100 women with a history of two or more miscarriages were enrolled, and serum samples were collected to test for the presence of anticardiolipin antibodies. Personal regarding age, parity and number of miscarriages was collected using a well-constructed questionnaire. Anticardiolipin antibodies IgG and IgM were assessed using the ELIZA technique. The findings reveal 48.0% positivity regarding anticardiolipin antibodies among the study group. Also, the study reflects a significant correlation between the presence of anticardiolipin and recurrent miscarriage suggesting a potentially underdiagnosed etiology of pregnancy loss. The results underscore the importance of early screening for antiphospholipid antibodies in women with a history of recurrent pregnancy loss.